About (early) clinical research

At the NKI Center for Early Clinical Research, we test new treatments or drugs in humans. Early clinical research is the first two phases of clinical research. The purpose of early clinical research is to see whether a treatment is safe, what dosage works well and what effect it has.

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The four phases of clinical research

Phase 1

The first tests are in a small group to see if the treatment is safe.

Phase 2

Testing in a larger group to investigate the effect on tumor growth and side effects.

Phase 3

Comparing the new treatment with the standard treatment in many patients.

Phase 4

Study after approval, to track long-term effects and rare side effects.

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